Stalagmometric titration

Coulometric Titration with Electrogenerated Tin(II). Titration of Platinum(IV)

Daytime CPAP Titration *

Objective: Continuous positive airway pressure (CPAP) is the treatment of choice for patients diagnosed with severe obstructive sleep apnea (OSA). The implementation of CPAP therapy has traditionally been based on full-night titration studies or split-night protocols. This study compared a group of patients who received a regular nocturnal CPAP titration with patients who received a daytime CPA...

Accelerated Titration Designs

A decade ago, investigators in oncology had a clear interest in modifications to the standard phase 1 design to make it more efficient, to treat fewer patients at non-toxic dose levels (which may be less efficacious), and to increase the precision of phase 2 dose recommendations. This was the conclusion of the 1996 joint meeting of the U.S. National Cancer Institute and the European Organizatio...

An automated titration system

Nevertheless there are two fundamentally different ways [2] of identifying sets of data. First, the cumulative collection of test results may be checked for plausibility. Mislabelled [3] results will be recognised if they differ greatly from those recorded earlier. The method, however, is not very effective as Sheiner et al [16] have shown. A Delta check method, [4] controlled by a computer, di...

A Coulometric-Titration Coulometer

A highly precise coulometer is described which permits time integration of currents totaling 100 coulombs or more with a precision of about 1 part in 100,000. The current to be integrated oxidizes hydroquinone in an electrolysis cell, producing quinone and acid. The quinone is t hen reduced by constant-current coulometric titration, the end point being indicated by hydrogen-ion concentration me...